Tolvaptan CAS 150683-30-0 API Hale Hana Kiʻekiʻe
Mea Hana Hana
ʻO ke kūlana kiʻekiʻe, ka hana kālepa
Inoa Kemika: Tolvaptan
CAS: 150683-30-0
| Inoa | Tolvaptan |
| Inoa Kimia | N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
| Helu CAS | 150683-30-0 |
| Helu CAT | RF-API101 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻAno Molekala | C26H25ClN2O3 |
| Kaumaha Molekala | 448.94 |
| Brand | Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keʻokeʻo a hiki i ka pauka kristal keʻokeʻo |
| Nā ʻano ʻike | IR, HPLC |
| ʻIke (HPLC) | 98.0~102.0% (ma ke kumu anhydrous) |
| Lae hehee | 219.0~222.0 ℃ |
| Nalo ma ka maloo | ≤0.50% |
| Koena ma ka Ignition | ≤0.10% |
| Hoʻokahi haumia | ≤0.50% |
| Huina paumaele | ≤1.0% |
| Metala Kaumaha | ≤20ppm |
| Nā mea hoʻoheheʻe koena | E hālāwai me ka wehewehe |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | Nā Kūwaena Lapaʻau |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
ʻO Tolvaptan (CAS 150683-30-0), i ʻike ʻia ʻo OPC-41061, he mea koho, hoʻokūkū arginine vasopressin receptor 2 antagonist i hoʻohana ʻia no ka mālama ʻana i ka hyponatremia (mau kiʻekiʻe o ka sodium koko haʻahaʻa) pili me ka puʻuwai congestive heart failure, cirrhosis, a me ka maʻi o ke kūpono ʻole. antidiuretic hormone (SIADH).ʻO Otsuka Pharmaceutical laikini tolvaptan ma lalo o ka inoa kālepa Samsca ma hope o ka ʻae ʻana o ka FDA i ka lāʻau lapaʻau i Mei 2009. Ua hōʻike pū ʻo Tolvaptan i ka maikaʻi e kūʻē i ka maʻi maʻi maʻi polycystic.Ma kahi hoʻokolohua 2004, ua ʻike ʻia ka tolvaptan me nā diuretics kuʻuna e hoʻonui i ka excretion o ka nui o ka wai a hoʻomaikaʻi i ke kiʻekiʻe o ka sodium koko i nā poʻe maʻi me ka puʻuwai puʻuwai me ka hana ʻole ʻana i nā hopena ʻaoʻao e like me ka hypotension (ke koko haʻahaʻa) a i ʻole hypokalemia (hōʻemi i ke kiʻekiʻe o ke koko o ka potassium).ʻAʻohe hopena maikaʻi ʻole o ka lāʻau lapaʻau i ka hana ʻāʻī.
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